This escape room will test your knowledge of cardiac electrophysiology (advanced), arrhythmias and ECGs. This game is suitable for students studying on healthcare professional courses, or for anyone with an interest in cardiac electrophysiology! The game can be played alone or as a group, and screen-sharing through video conferencing platforms can be used if a group of individuals wish to play remotely. Before starting the game, please ensure that you have read all the information provided below and that you have watched the introductory video.


The game consists of a series of “locks”. To work out the code for each lock, you will need to solve a puzzle that will draw on your knowledge of cardiac electrophysiology. Once you have opened the first lock, a button will be revealed allowing access to the next puzzle. You will have 60 minutes to solve the puzzles, escape the room and win the game. 


Clues will be provided, but to get the most out of the exercise, you should try to solve the puzzles to the best of your ability before using them!


Please read before you start!


  • The escape room is supported by the following browsers: Chrome, Firefox and Safari. It is NOT supported by Microsoft Edge.
  • DO NOT use your browser’s back button or page refresh while the game is in play as this will interrupt the gaming sequence.
  • The game has been designed to be played on larger screens (e.g. desktop/laptop). Functionality cannot be guaranteed on mobile devices.
  • If the scroll function stops working on the page, use your mouse cursor to move the scroll bar (right hand side) or the keyboard arrow keys



  • The puzzles are interactive, so feel free to click around as clues may be hidden.
  • The codes for the locks can be letters or numbers, but all are lowercase and you should include spaces where appropriate. 
  • Clues are provided below each puzzle to help if you get stuck. Try and solve the puzzles to the best of your ability BEFORE using them.
  • Be ready to start the game as soon as you click the button below. The clock will start as soon as the page loads!
This resource was created at Keele University and funded by The Physiological Society (David Jordan Teaching Award). 


First published in February 2022. Updated in December 2022.